Bone Marrow Infiltration as the Primary Manifestation of Metastasic Melanoma: A Rare Case Report
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References
I. Joshi UM, Kashani-Sabet M, Kirkwood JM. Cutaneous Melanoma: A Review. JAMA. 2025 Dec 16;334(23):2113-2125.
doi: 10.1001/jama.2025.13074.
II. Helvind NM, Brinch-Møller Weitemeyer M, Chakera AH, Hendel HW, Ellebæk E, Svane IM, et al. Stage-Specific Risk of Recurrence and Death From Melanoma in Denmark, 2008-2021: A National Observational Cohort Study of 25 720 Patients With Stage IA to IV Melanoma. JAMA Dermatol. 2023 Nov 1;159(11):1213-1222.
doi: 10.1001/jamadermatol.2023.3256.
III. Paolino G, Carugno A, Rongioletti F, Ponzoni M, Russo V, Sena P, et al. Bone marrow metastases: a systematic review of a neglected involvement in malignant melanoma. Melanoma Res. 2024 Feb;34(1):31-37.
doi: 10097/CMR.0000000000000942
IV. Kaspi E, Grosdidier C, Berda-Haddad Y, Arpin M, Cointe S, Fritz S, et al. Challenges and Clinical Relevance in Diagnosing Metastatic Cells From Non-Hematopoietic Malignancies in Bone Marrow Aspirates. Cancer Med. 2025 Feb;14(3):e70645. doi: 10.1002/cam4.70645.
V. Mundada M, Zhong X, So A, et al. Clinical and Pathologic Factors in Stage I and II Melanoma Recurrence. JAMA Dermatol. 2026;162(4):378-385. doi:10.1001/jamadermatol.2026.0001
VI. Suzuki T, Kusumoto S, Iida S, Tada T, Mori F. Amelanotic malignant melanoma of unknown primary origin metastasizing to the bone marrow: a case report and review of the literature. Intern Med. 2014;53(4):325-328.
doi: 10.2169/internalmedicine.53.1412.