Case Report of a Patient With Fournier's Gangrene
Main Article Content
Abstract
Fournier's gangrene is a life-threatening necrotizing fasciitis affecting the soft tissues of the perineal, genital, and perianal regions. It progresses rapidly due to microvascular thrombosis and extensive tissue necrosis. The condition occurs more frequently in men and is associated with comorbidities such as diabetes mellitus, alcoholism, immunosuppression, obesity, and chronic kidney disease. Its polymicrobial etiology, involving both aerobic and anaerobic bacteria, promotes tissue destruction and sepsis. Management requires a multidisciplinary approach including hemodynamic resuscitation, broad-spectrum antibiotic therapy, and aggressive repeated surgical debridement.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
I. Sorensen, M. D., Krieger, J. N., Rivara, F. P., Broghammer, J. A., Klein, M. B., & Mack, C. D. (2009). Fournier’s Gangrene: Population based epidemiology and outcomes. The Journal of Urology, 181(5), 2120–2126.
II. Eke, N. (2000). Fournier’s gangrene: A review of 1726 cases. British Journal of Surgery, 87(6), 718–728.
III. Hagedorn, J. C., & Wessells, H. (2017). A contemporary update on Fournier’s gangrene. Nature Reviews Urology, 14(4), 205–214.
IV. Fournier JA. Gangrene foudroyante de la verge. Sem Med. 1883;3:345-8.
V. Sorensen MD, Krieger JN. Fournier's gangrene: epidemiology and outcomes in the general US population. Urol Int. 2016;97(3):249-59.
VI. Yanar H, Taviloglu K, Ertekin C, Guloglu R, Zorba U, Cabioglu N, et al. Fournier's gangrene: risk factors and strategies for management. World J Surg. 2006;30(9):1750-4.
VII. Stevens DL, Bryant AE. Necrotizing soft-tissue infections. N Engl J Med. 2017;377(23):2253-65.
VIII. Lin TY, Ou CH, Tzai TS, Tong YC, Chang CC, Cheng HL, et al. Validation and simplification of Fournier's Gangrene Severity Index. Int J Urol. 2014;21(7):696-701.