Multiple Bilateral Fibroadenomas Associated with A Benign Phyllodes Tumor in a Young Patient: A Case Report
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Abstract
Introduction: Fibroadenomas are the most common benign tumors of the breast; however, their presentation as multiple and bilateral lesions is uncommon, particularly in young patients. Coexistence with a benign phyllodes tumor is exceptional and poses diagnostic and therapeutic challenges.
Case presentation: We report the case of an 18-year-old woman with intellectual disability who presented with multiple painful bilateral breast masses of eight months’ duration. Physical examination revealed approximately ten bilateral breast nodules. Breast ultrasonography demonstrated multiple oval lesions with circumscribed margins, classified as BI-RADS 3. Due to the multiplicity, size of the lesions, and associated symptoms, surgical management was chosen without prior biopsy. Complete resection of the lesions was performed through a single circumferential periareolar incision using the round-block technique. Histopathological examination revealed multiple bilateral pericanalicular fibroadenomas and three benign phyllodes tumors with negative surgical margins. Postoperative evolution was favorable, with complete resolution of pain and no complications. Clinical and imaging follow-up at 3 and 6 months showed no recurrence.
Conclusion: This case illustrates an uncommon presentation of multiple bilateral fibroadenomas associated with benign phyllodes tumors in a young patient. Conservative surgical management using the round-block technique allowed adequate resection with favorable clinical and aesthetic outcomes. The importance of an individualized diagnostic approach and close follow-up in rare presentations of fibroepithelial breast tumors is emphasized.
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References
I. Eni, U. E., Isikhuemen, M. E., Eliboh, M. O., Sunday-Adeoye, I., Ekwedigwe, K. C., & Lengmang, S. (2017). Case report of multiple breast fibroadenomas in a young Nigerian woman. Revista Brasileira de Mastologia, 27(1), 16–19
https://doi.org/10.5327/Z201700010016RBM
II. Zhang, R. R., Bevan, S., Sun, P., Lu, J. Z., & Peng, Y. (2012). Unusual presentation of multiple fibroadenomas in bilateral breasts and accessory axillary breast. Breast Cancer: Basic and Clinical Research, 6, 95–99.
https://doi.org/10.4137/BCBCR.S9512
III. Conde, D. M., Morais, L. C., Pacheco, C. F., Ferreira, R. B., Sousa-e-Silva, É. P., Fonseca, P. S. P., & Pinto, S. A. (2017). Multiple bilateral breast fibroadenomas and accessory axillary breast: A case report. Revista Brasileira de Ginecologia e Obstetrícia, 39(2), 75–79.
IV. Im, C. J., Miller, A., Balassanian, R., & Mukhtar, R. A. (2021). Early-onset, multiple, bilateral breast fibroadenomas: A case report. BMC Women’s Health, 21(1), Article 170.
https://doi.org/10.1186/s12905-021-01311-7
V. Nikumbh, D. B., Desai, S. R., Madan, P. S., Patil, N. J., & Wader, J. V. (2011). Bilateral giant juvenile fibroadenomas of the breast: A case report. Pathology Research International, 2011, Article 482046.
https://doi.org/10.4061/2011/482046
VI. Santiago-Sanabria, L., López-Valle, M. Á., Garza-Arrieta, J., et al. (2022). Bilateral phyllodes tumor: A rare form of clinical presentation. Case report. Ginecología y Obstetricia de México, 90(11), 933–941.
VII. Panda, S. K., Patro, B., Mishra, J., Dora, R. K., & Subudhi, B. S. K. (2014). Multiple fibroadenomas in bilateral breasts in a 46-year-old Indian woman: A case report. International Journal of Surgery Case Reports, 5(5), 262–264.
https://doi.org/10.1016/j.ijscr.2013.12.013
VIII. Lovasić, F., Petković, M., Belac-Lovasić, I., Mustać, E., Uravić, M., & Zelić, M. (2011). The “round-block” surgical technique in the management of multicentric fibroadenomas. Collegium
Antropologicum, 35(1), 235–240