Involutive Congenital Tufted Angioma, an Atypical Case Presentation
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Abstract
A case is presented of a 3-month-and-15-day-old male patient referred for a consultation due to a congenital 'red spot' on the left abdomen, where a linear erythematous-violaceous plaque with gray areas, indurated texture, and fine hairs was observed.
An ultrasound was requested, revealing findings consistent with an infiltrative lesion. A biopsy was performed, and the lesion was reported as compatible with tufted angioma, reactive for immunohistochemical markers CD31, CD34, and D2-40. A description of the case is provided, along with a bibliographic review, emphasizing the clinical presentation and diagnostic approach.
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References
I. Feito-Rodríguez M, Sánchez-Orta A, De Lucas R, López-Gutiérrez JC, Ruiz-Bravo E, Baselga E, et al. Congenital tufted angioma: A multicenter retrospective study of 30 cases. Pediatr Dermatol [Internet]. 2018;35(6):808–16. Available from: http://dx.doi.org/10.1111/pde.13683
II. Osio A, Fraitag S, Hadj-Rabia S, Bodemer C, de Prost Y, Hamel-Teillac D. Clinical spectrum of tufted angiomas in childhood: a report of 13 cases and a review of the literature: A report of 13 cases and a review of the literature. Arch Dermatol [Internet]. 2010;146(7):758–63. Available from: http://dx.doi.org/10.1001/archdermatol.2010.135
III. Victoria Martínez AM, Cubells Sánchez L, Esteve Martínez A, Estela Cubells JR, Febrer Bosch I, Alegre de Miquel V, et al. Angiomas en penacho en la infancia. Serie de 9 casos y revisión de la literatura. An Pediatr (Barc) [Internet]. 2015;83(3):201–8. Available from: http://dx.doi.org/10.1016/j.anpedi.2014.10.018
IV. Browning J, Frieden I, Baselga E, Wagner A, Metry D. Congenital, self-regressing tufted angioma. Arch Dermatol [Internet]. 2006;142(6):749–51. Available from: http://dx.doi.org/10.1001/archderm.142.6.749
V. Le Huu AR, Jokinen CH, Rubin BP, Mihm MC, Weiss SW, North PE, et al. Expression of prox1, lymphatic endothelial nuclear transcription factor, in Kaposiform hemangioendothelioma and tufted angioma. Am J Surg Pathol [Internet]. 2010;34(11):1563–73. Available from: http://dx.doi.org/10.1097/PAS.0b013e3181f6076f
VI. Sadeghpour M, Antaya RJ, Lazova R, Ko CJ. Dilated lymphatic vessels in tufted angioma: a potential source of diagnostic confusion. Am J Dermatopathol [Internet]. 2012;34(4):400–3. Available from: http://dx.doi.org/10.1097/DAD.0b013e318234e720
VII. Le Huu R, Jokinen A, Ruben CH. Expression of Prox1, lymphatic endothelial nuclear transcription factor, in kaposiform hemangioendothelioma and tufted Angioma Am. J Surg Pathol. 2010;34:1563–73.
VIII. Silva CM da, Schettini APM, Santos M, Chirano CAR. Tufted angioma. An Bras Dermatol [Internet]. 2017;92(5):742–3. Available from: http://dx.doi.org/10.1590/abd1806-4841.20175896
IX. Tufted angioma: A picture not to forget. J Am Acad Dermatol [Internet]. 2018;79(3):AB304. Available from: http://dx.doi.org/10.1016/j.jaad.2018.05.1202
X. Goss JA, Greene AK. Congenital vascular tumors. Otolaryngol Clin North Am [Internet]. 2018;51(1):89–97. Available from: http://dx.doi.org/10.1016/j.otc.2017.09.008
XI. Lim YH, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, et al. GNA14 somatic mutation causes congenital and sporadic vascular tumors by MAPK activation. Am J Hum Genet [Internet]. 2016;99(2):443–50. Available from: http://dx.doi.org/10.1016/j.ajhg.2016.06.010
XII. Rambhia KD, Khopkar US. Tufted angioma. Indian Dermatol Online J [Internet]. 2016;7(1):62–3. Available from: http://dx.doi.org/10.4103/2229-5178.174313
XIII. Pfister BK, King EC, Samet JD, Gulliver J, Wolf SF. Tufted angioma of the index finger middle phalanx. J Am Acad Orthop Surg Glob Res Rev [Internet]. 2022;6(7). Available from: http://dx.doi.org/10.5435/JAAOSGlobal-D-21-00301
XIV. Liu XH, Li JY, Qu XH, Yan WL, Zhang L, Yang C, et al. Treatment of kaposiform hemangioendothelioma and tufted angioma. Int J Cancer [Internet]. 2016;139(7):1658–66. Available from: http://dx.doi.org/10.1002/ijc.30216